Streptomycin Dosage Calculation: Ensuring Precision in Healthcare

In the realm of healthcare, precise medication administration is paramount for delivering optimal patient care. This article dives into the method for accurately calculating and administering the correct dosage of streptomycin, as per a healthcare provider’s prescription. The healthcare provider has directed the administration of streptomycin at a dosage of 1.75 mg per pound via intramuscular (IM) injection every 12 hours. The available streptomycin concentration is 0.35 grams per 2.3 mL. To ensure patient well-being and effective treatment, it is essential to understand the prescription, the available medication form, and the intramuscular injection technique.

Understanding Streptomycin Dosage and Intramuscular Administration

Streptomycin is an antibiotic medication used to treat various bacterial infections. When calculating the appropriate dosage for patients, healthcare professionals must consider the prescribed dose and the chosen route of administration, which, in this case, is intramuscular injection.

Interpreting Healthcare Provider’s Prescription

The instructions provided by the healthcare provider are instrumental in determining the correct medication dosage:

  • Medication: Streptomycin
  • Prescribed Dose: 1.75 mg per pound
  • Route: Intramuscular (IM)
  • Frequency: Every 12 hours
  • Medication Concentration: 0.35 grams per 2.3 mL

Method for Calculating the Streptomycin Dosage

To calculate the precise dosage, healthcare professionals must consider the prescribed dose and the medication’s concentration, while also accounting for the patient’s weight:

  1. Calculate the patient’s daily dosage in milligrams:

    Daily Dosage (mg) = Prescribed Dose (mg/lb) x Patient’s Weight (lb)

  2. Determine the volume (mL) to be administered for each dose:

    Volume per Dose (mL) = Daily Dosage (mg) / Medication Concentration (mg per mL)

Safe Intramuscular Injection Administration

When providing instructions on intramuscular injection administration, healthcare professionals should ensure adherence to the following steps:

  1. Confirm that the caregiver or patient has the prescribed streptomycin, a clean and appropriate syringe, and access to the necessary supplies for correct injection technique.
  2. Emphasize the importance of following the prescribed dosage and preparing the intramuscular injection accurately.
  3. Provide guidance on the correct injection site, technique, and any specific instructions given by the healthcare provider.
  4. Highlight the significance of maintaining the dosing schedule and adhering to the specified frequency and timing of streptomycin administration.

Precision in Dosage Calculation and Patient Treatment

Accurate calculation and administration of streptomycin are fundamental in healthcare to ensure the successful treatment of bacterial infections. Healthcare professionals must ensure that the prescribed dosage and injection technique are meticulously followed to guarantee patients receive the appropriate amount of streptomycin needed for effective treatment while minimizing the potential for complications.


Ensuring the precise administration of streptomycin via intramuscular injection is pivotal for effective patient treatment in healthcare. By adhering to healthcare provider instructions and considering factors such as the medication’s concentration and the patient’s weight, healthcare professionals can guarantee patients receive the correct amount of streptomycin required for optimal treatment, ultimately contributing to their well-being and recovery in healthcare practice.


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